Black nightshade (Solanum americanum; also, Solanum nigrescens).

Plant Part Used: Leaf.

Dominican Medicinal Uses: Leaf: decoction, orally, for allergies, vaginal infections, cysts, fibroids, cancer (early stages), blood-cleansing, childbirth and postpartum recovery.

Safety: Leaf extracts in moderate amounts have shown relatively low toxicity; in excess, can cause adverse reactions; fruits contain toxic alkaloids.

Clinical Data: Human clinical trials: treatment of vaginal candidiasis (plant extract).

Laboratory & Preclinical Data: In vivo: immunomodulatory (leaf extract).

In vitro: antidermatophytic, antifungal (plant extract); antimicrobial (leaf extract); antitrypanosomal (plant extract).

* See entry for Hierba mora in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.

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